​What is Pathology - What is gangrenous inflammation, and what causes it?

​What is Pathology - What is gangrenous inflammation, and what causes it?​ When bacteria infect necrotic tissue, gangrene develops. Diabetics with diabetic microangiopathy and accelerated atherosclerosis typically experience similar inflammation on their legs, resulting in hypoperfusion of the extremities. An infarcted gut can potentially cause gangrene. Saprophytic bacterium, which is generally present at the site of ischemic tissue necrosis, causes infection in both cases.