What is Pathology - ​Which modifications in the mitochondria are irreversible?

What is Pathology - ​Which modifications in the mitochondria are irreversible? 
The enlargement of mitochondria is a reversible process. The following are examples of irreversible changes: 
a) Fragmentation 
b) Rupture of double membrane 
c) Myelin figures (concentric curling up of damaged membranes) &
d) Calcification Mitochondria that have been damaged are picked up by autophagosomes and degraded.