What is Endocrinology - . After beating Graves' disease, this female track champion went on to earn the "Fastest Woman in the World" title in the 1992 Summer Olympics in Barcelona. She is who?
Gillian Devers At the Atlanta Olympics in 1996, Devers won the women's 100-meter race again. She had an incredibly long career in her sport. She won the 60-meter hurdles event at the Melrose Games in February 2007 at the age of 40 with a time of 7.86 seconds.
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What is Endocrinology - . Who was the former Gonzaga University star in college basketball who was given a type 1 diabetes diagnosis at the age of 14?
Morrison, Adam. Morrison and Duke's J.J. Redick split the Player of the Year award in college basketball following his last year of competition. The Charlotte Bobcats later picked him third overall in the 2006 National Basketball Association (NBA) draught. What is Endocrinology - How does obstructive sleep apnea (OSA) affect the testosterone panel?9/25/2022 What is Endocrinology - How does obstructive sleep apnea (OSA) affect the testosterone panel?
Does OSA therapy affect the panel's decision? The androgen alterations associated with OSA differ from those brought on by ageing and fat . Sex hormone-binding globulin, free, and total testosterone levels drop in OSA without concurrent gonadotropin increases. In fact, an untreated OSA was associated with LH pulse abnormalities in one research. When OSA is treated, whether with CPAP or uvulopalatopharyngoplasty, testosterone levels rise. These results suggest that reduced testosterone levels in untreated OSA are caused by a hypothalamic mechanism. What is Endocrinology - What impact do androgens have on sleep?
Exogenous testosterone may cause sleep apnea-related alterations or exacerbate OSA that already exists. A high-dose testosterone injection in hypogonadal older men who were otherwise healthy and had undiagnosed sleep apnea reduced total sleep time and made it worse, according to one randomised controlled experiment. Despite the fact that there have been no confirmed reports linking hypogonadism to diminished cognition and impaired driving, it is the prescriber's responsibility to check patients for the risk of undiagnosed OSA. What is Endocrinology - Is the testosterone loss seen with ageing linked to alterations in aging-related sleep patterns?
It most likely is. As was previously mentioned, ageing is linked to shorter sleep and SWS durations. LH pulses in older males have a smaller amplitude but a higher frequency. Although it is less pronounced and no longer correlated with the time to the first REM episode, the testosterone surge linked with sleep is still evident. What is Endocrinology - What impact does lack of sleep have on the hunger and satiety hormones, ghrelin and leptin?
Leptin levels drop with sleep deprivation whereas ghrelin levels rise (from the root ghre, which means "to grow"). Leptin levels rise and ghrelin levels fall during extended periods of sleep. Leptin release is known to be reduced in sleep deprived individuals, and during a 6-month period, sleep deprived individuals gain an average of 10 pounds more than do rested individuals. What is Endocrinology - What impact does lack of sleep have on the hunger and satiety hormones, ghrelin and leptin?
Leptin levels drop with sleep deprivation whereas ghrelin levels rise (from the root ghre, which means "to grow"). Leptin levels rise and ghrelin levels fall during extended periods of sleep. Leptin release is known to be reduced in sleep deprived individuals, and during a 6-month period, sleep deprived individuals gain an average of 10 pounds more than do rested individuals. What is Endocrinology - Does weight loss occur in obstructive sleep apnea (OSA) patients who use CPAP effectively?
Yes, it does, and reportedly via two different processes. First, people with sleep apnea who receive treatment typically wake up feeling better rested and more energised. Patients with OSA have even been shown to exercise more after starting treatment. Second, treating sleep apnea causes serum leptin, or "satiety hormone," to return to normal levels. Leptin is derived from the Greek word leptos, which means "thin." Leptin is suppressed by sleep loss and untreated sleep apnea, as covered in the following question. What is Endocrinology - How effectively do healthcare professionals in diabetic clinics screen patients for obstructive sleep apnea (OSA)?
What are effective tools for history- and physical-based screening? 56% of diabetic patients reported snoring, 29% had weariness upon awakening, and 34% reported feeling tired while awake, according to a study that used a validated clinical assessment and questionnaire to estimate OSA risk and drowsiness. 56% of individuals surveyed, according to the study's authors, had a high risk of developing OSA. Given the high prevalence of SDB reported in the diabetic patient population, this finding supports a recommendation for increased vigilance in the screening for OSA in this patient population. To do this, a few screening tools might be useful. The risk of OSA is inversely correlated with BMI; the most delicate physical finding is a neck size more than 17 inches. Patients who have certain craniofacial alterations, such retrognathia, are also at a higher risk. A patient with OSA is frequently ignorant of the neurocognitive changes that have gradually taken place over time, thus unless specifically asked, he or she may not readily provide a history that is consistent with OSA. What is Endocrinology - Does the use of continuous positive airway pressure (CPAP) improve aberrant glucose metabolism parameters with regard to causality?
Yes. Patients without diabetes, diabetics who are not obese, and those with poorly controlled diabetes all exhibit this. Warning: In this body of work, it is up to the reader to determine from the trial if a documented CPAP compliance measure was used. Trials that report CPAP adherence definitions and those that show no change in BMI over the course of the research do demonstrate improvement. After just two days of treatment, CPAP dramatically improved insulin sensitivity in a study of non-diabetic patients with moderate to severe OSA, and the improvement sustained at the 3-month follow-up with no appreciable changes in body weight. The non-obese patients showed the strongest effects of this factor. In contrast, patients with DM2 who were obese did not exhibit any improvement in insulin sensitivity in this research lab. In other studies, patients with DM2 and OSA experienced the greatest postprandial blood glucose level improvements following CPAP therapy. |
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