​What is Dermatology - What structural components of the basement membrane are involved in the development of bullous skin diseases?

​What is Dermatology - What structural components of the basement membrane are involved in the development of bullous skin diseases?  
Structures within the basement membrane can be congenitally absent or reduced in quantity, or they can be damaged by antibodies directed against them, as with epidermal desmosomes. Hemidesmosomes attach the basal keratinocytes to the basement membrane in the uppermost region of the BMZ, the lamina lucida. Antihemidesmosomal antibodies are produced in bullous pemphigoid, an acquired blistering condition. These antibodies appear to cause inflammation and hemidesmosome destruction, resulting in a blister between the cells and the basement membrane.