What is Emergency Medicine - Which hemostatic medications are most frequently used?
• Combat gauze from QuikClot. The US military chooses this product first when looking for hemostatic medications. The intrinsic clotting cascade is triggered by a nonexothermic mineral component (kaolin) embedded in gauze. Large clots should be removed as soon as possible, the cause of the bleeding should be found, and the area should be packed with gauze. The gauze should be placed directly on the bleeding vessel(s) and held in place with direct pressure for at least three minutes to guarantee maximum effectiveness. Combat gauze that has become saturated should be removed and replaced with fresh agent-infused gauze. • Celox. chitosan, a polysaccharide made from shellfish. It creates a gel-like substance when in contact with blood, which helps clots form. It has the advantage of operating independently of the clotting cascade but was shown to be slightly less effective than military gauze. As a result, it works well for patients who have coagulopathies brought on by anticoagulants and hypothermia. • ChitoGauze HemCon. It operates similarly to Celox and is a chitosan derivative. It is offered in a gauze form, similar to other agents, to make packing wounds easier.
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