What is Endocrinology - What are the signs that Paget's illness has to be treated?
The presence of symptoms is the main cue for treatment. Not all symptoms, nevertheless, are treatable. Both bone pain and some neurologic compression symptoms typically react. Conversely, therapy is unlikely to help with hearing loss, bone abnormalities, or mechanically unsound joints. The prevention of local progression, planned surgery at a pagetic site, widespread pagetic involvement in patients who will likely be immobilised for an extended period of time (to reduce the risk of hypercalcemia), and potential prevention of future complications are additional indications for treating Paget's disease. It is debatable how to handle asymptomatic Paget's disease patients. Untreated Paget's illness, however, seems to worsen over time, and not all asymptomatic patients stay that way. As a result, many doctors treat patients with osteolytic Paget's disease or asymptomatic patients with an active disease affecting the skull, vertebral bodies, or bones that bear weight
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