What is Endocrinology - What is osteonecrosis of the jaw, and does it occur in Paget's disease patients on bisphosphonates?
A region of exposed bone in the maxillofacial region that lasts longer than six weeks is known as osteonecrosis of the jaw (ONJ). Usually, this problem develops after dental surgery. The symptoms might range from sharp jaw discomfort to a painful exposed bone. Although there have been a few cases of this syndrome happening in people with Paget's disease, ONJ has also been recorded in patients taking extended intravenous bisphosphonates for cancer. So, using bisphosphonates to treat Paget's disease shouldn't be restricted due to the risk of ONJ. However, it is advised that bisphosphonate medication be postponed until after anticipated significant dental procedures or oral surgery is finished. Routine dental exams and oral care should be provided to all individuals using bisphosphonates.
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