What is Endocrinology - Why do people with hypothyroidism frequently have yellow skin?
The top layer of the epidermis's yellow tint is caused by an overgrowth of carotene (carotenoderma) (stratum corneum). Carotene tends to concentrate on the palms, soles, and face and is expelled through sweat and sebaceous glands. The elevated levels of beta-carotene are most likely a result of the liver's inability to convert beta-carotene to vitamin A.
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