What is ENT - . How is the diagnosis of medullary thyroid carcinoma handled?
MEN type II tumour screening should be performed on patients who have the RET mutation: (2) Parathyroid adenoma: serum calcium and parathyroid hormone and (1) pheochromocytoma: plasma fractionated metanephrines and abdomen scan to rule out pheochromocytoma (PTH). Family members ought to undergo genetic testing for MEN type II cancers and the RET protooncogene. Depending on the levels of calcitonin and CEA, imaging should assess both local and distant metastases using computed tomography (CT) or magnetic resonance imaging (MRI). High CEA or calcitonin values suggest distant metastases and may warrant further imaging.
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