What is ENT - What distinctive features of medullary thyroid carcinoma are significant?
• More aggressive than papillary and follicular thyroid tumours, which have a good degree of differentiation Prostaglandins, histaminases, serotonin, calcitonin, and carcinoembryonic antigen (CEA) can all be secreted by these cells, which are derived from parafollicular or C cells. They also have a high propensity to invade muscle and the trachea and to spread hematogenously to the lungs and viscera (50% at presentation). • MEN IIb type is the most aggressive; familial medullary thyroid cancer has the greatest prognosis, and MEN IIa has an intermediate prognosis. Sporadic unifocal lesions account for 70% of cases, whereas familial/genetic cases account for 30%.
0 Comments
Leave a Reply. |
Kembara's Health SolutionsDiscovering the world of health and medicine. Archives
June 2023
Categories
All
|