What Is Microbiology - Erythema Infectiosum

Erythema infectiosum 
Erythema infectiosum is also known as fifth disease. Erythema infectiosum is presented with slapped cheek appearance in children. The child may present with generalized erythematous rash on the face.  

Erythema infectiosum is caused by parvovirus B19. Parvovirus B 19 is detected via PCR detection and detection of the B-19 specific IgM antibody. 

In adult parvovirus B19 infection may lead to arthritis and arthralgia. Pregnant women who predispose to parvovirus B 19 may present with generalized fetal anemia and congestive heart failure or known as hydrops fetalis. 

Parvovirus B 19 will be transmitted via respiratory droplets. Parvovirus B 19 will lead to proliferation of the hematopoietic cells due to the infection of the erythroid precursors in the bone marrow. Parvovirus B 19 may cause anemia and suppression of the erythropoiesis due to parvovirus B 19 cytolytic properties on immature erythroid cells. 

Aplastic crisis is commonly present due to parvovirus B19 infection in sickle cell disease or hemolytic anemia patient.