What is Pathology - Sjögren’s Syndrome
Pathophysiology • An autoimmune disease in which T lymphocytes and autoantibodies target the salivary and lacrimal glands. • May exist alone or in conjunction with other autoimmune illnesses. • Older women are the primary demographic affected. Non-Hodgkin cancer risk is increased by 40%–60% in individuals with Sjögren's syndrome. Evaluation and Diagnostic Results • Blurred vision, burning, itching, and the capacity to wet a test strip positioned beneath the eyelid in the Schirmer's test. • Dry nasal membranes, thick secretions in the bronchi and lungs, dysphagia, dry, cracked oral mucous membranes, enlarged parotid glands, lower lip salivary biopsy, decreased perception of taste, thick secretions, thick secretions in the bronchi and lungs. • Vasculitis, recurrent Candida infections and vaginal dryness. • Elevated ESR, leukopenia, and anaemia. Anorexia, non-Hodgkin's lymphoma, dyspareunia, palpitations, and primary biliary cirrhosis are among the complications. medical attention and surgical procedure • Artificial tears, cyclosporine eye drops, comprehensive and effective oral hygiene, sugarless gum or sweets, sips of water, cholinergic saliva-inducing medication, and artificial saliva. • Immunosuppressants and antimalarial drugs. • Report persistent dry eye, dysphagia, and xerostomia. • Check your capacity to ingest. • Prevent ocular abrasion by shielding eyes from extreme dryness.
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