What is Pathology - What are eosinophils and what do they do?
Eosinophils can play a role in acute processes, but they are more prevalent in chronic ones. The following are the main roles of eosinophils:
- Bactericidal effect: Eosinophils enter at the infection site later than neutrophils, but they stay longer. They are less effective at killing germs than neutrophils or macrophages. As a result, they are referred to as the phagocytes"slower and less efficient cousins."
- Antiparasitic action: Eosinophils have crystalloid granules rich with parasite-killing proteins such as major basic protein (MBP), eosinophilic cationic protein (ECP), and others. Eosinophils are commonly found in parasite-induced infiltrates.
-Allergy to foreign antigens: Eosinophils are involved in allergic reactions to foreign antigens. Atopic (type I hypersensitivity) reactions, such as hay fever and asthma, are the most common. Mast cells, which are the principal reactants to foreign antigens in these disorders, are hypothesised to be counterbalanced by them.
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