What is Pathology - What are myelin figures, and what do they mean?
Electron microscopy reveals myelin patterns, which are cytoplasmic structures found in injured cells. They're made up of concentric whorls of membranes formed from cytoplasmic organelles like mitochondria or RER that have been destroyed. In Tay-Sachs disease and other inborn metabolic defects that damage the cytoplasmic membranes, myelin figures are prevalent in neurons. Myelin figures, like other remnants of damaged organelles, are sucked up by autophagosomes.
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