What is Pathology -What causes cell injury in hypoxia?
Aerobic respiration requires the presence of oxygen. Hypoxia inhibits normal oxidative phosphorylation, lowering mitochondrial capacity to produce adenosine triphosphate (ATP). The cell's vital processes cannot be maintained without ATP. Hypoxic cells inflate as a result of the lack of oxygen. This is referred to as a hydropic or vacuolar alteration, and it is usually reversible.
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