What is Pathology - What happens when you have necrosis?
Restitution in full: The deceased cells are replaced by nearly parenchymal cells in a process known as regeneration. Organs made up of facultative mitotic cells, such as the kidneys and liver, regenerate.
Repair: Fibrous tissue replaces the deceased cells, leaving microscopic or macroscopic scars. In the heart, for example, phagocytes remove dead myocardial cells and replace them with a fibrous scar.
Calcification: The necrotic tissue is sometimes contaminated with calcium salts (dystrophic calcification).
Resorption of necrotic tissue: Macrophages in the brain remove necrotic tissue, transforming the infarct into a fluid-filled pseudocyst.
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