What is Pathology - What is the definition of fat necrosis?
Fat cells in and around the pancreas, the omentum, and the abdominal cavity wall are commonly involved. It is characterised by lipolysis, which happens when lipase and other lytic enzymes released from injured pancreas cells infiltrate fat cells. Acute pancreatitis is the most common cause of this. The fat tissue appears squishy and fluid at first, but it eventually turns into chalky white patches made up of calcium soaps. Fat cells lose their shapes and become blurry histologically. Calcium deposition gives necrotic fat cells a bluish tint.
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