What is Pathology - When it comes to selectins and integrins, what's the difference?
Selectins are proteins that bind exclusively to carbohydrates and are found on the surfaces of leukocytes, platelets, and endothelial cells. On the other hand, integrins are only found on leukocytes. They bind to immunoglobulin family intercellular adhesion molecules (e.g., ICAM-1 and VCAM-1) as well as extracellular matrix (ECM) molecules like fibronectin and laminin.
Kembara's Health Solutions
Discovering the world of health and medicine.