Hydralazine is useful in treating patient with hypertension. Mostly pregnant woman with severe hypertension. Allergic reaction may occur due to long term use of hydralazine.
Hydralazine is a vasolidator which is given orally. Hydralazine will cause relaxation of the smooth muscle of the artery which lead to the lowering of the blood pressure. Hydralazine will affect the release of the calcium ion from the sarcoplasmic reticulum which present in the smooth muscle cells of the vascular system. The half life of hydralazine is 1-3 hours.
The common side effects with hydralazine may include hypotension, dizziness and gastrointestinal disturbance as well as palpitations.
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